Mouth-Dissolving Films: A Novel Approach for Oral Drug Delivery in Diabetic Management

Abstract

For the administration of several pharmacologicals, the oral route is considered one of the most practical methods of drug administration, as it accommodates various dosage forms, including tablets, syrups, capsules, emulsions, and suspensions. Mouth Dissolving Drug Delivery Systems have created several fast-dissolving preparations, such as MDT and mouth dissolving film. The hydrophilic polymer makes oral thin films, an innovative dosage form designed to dissolve quickly in the buccal cavity. when it is placed in the mouth, because it is less expensive to produce, mouth dissolving film is better than mouth dissolving tablets. Oral films help overcome swallowin difficulties commonly experienced by both elderly and paediatric patients with tablets and capsules. It also has other benefits, including self-administration and rapid dissolution. This dosage form allows for rapid absorption, making it highly versatile. The current study aims to highlight various polymers, their concentrations, and their applications. Additionally, it explores the role of plasticizers, sweeteners, polymers, and different techniques used in the formulation of oral films, along with the key parameters for their evaluation.[1].